December 19th, 2010 by admin
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http://www.moriarty.com/depuy_hip_recall/Stay_Informed/What_is_Metallosis/ |
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What is Metallosis? |
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| A Moriarty Leyendecker case site. Visit Moriarty.com for more information. DePuy Hip Recall Stay Informed In The News Crib Sheets Our Attorneys FAQs Search Tips Stay Informed » Subscribe to this feed. What is Metallosis? Metallosis occurs when metallic debris builds up in the periprosthetic soft tissues. In the case of the DePuy ASR Acetabular system, the two parts of the hip implant abraded against one another, creating friction and releasing metallic ions of cobalt and chromium into the body. Those microscopic metal ions cause an autoimmune response. The immune system identifies the metal ions as foreign bodies and automatically inflames the area around the debris. The body is essentially trying to trap the foreign particles in the inflamed area so that the metal can’t spread to the rest of the body. In the case of the DePuy hip implant, it appears that the immune system sends inflammatory cells to the synovial membrane as well, causing synovitis. Synovitis is generally quite painful, since the membrane is too inflamed to allow the joint to rotate properly. Metallosis can be complicated by metal sensitivity, which is essentially an allergic reaction to metal. The normal autoimmune response to foreign matter in the body is to inflame the area and attack the foreign cells. When the body is hypersensitive to a |
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